|
|
|
|
|
| Al-Olayan,Ebtesam M; Mohamed,Aly F; El-Khadraqy,Manal F; Shebl,Rania I; Yehia,HanryM. |
| ABSTRACT Vaccine improvement depends on the formulation, adjuvant type and inactivant used. The type of formulation may interfere with immunogenicity. The present work aimed to evaluate the inactivation activity and related immune potential of the Cobra venom-derived LAO enzyme compared to the currently used inactivants (BPL and formalin) for both animal and human vaccines. The RVF virus was completely inactivated within 6 hrs, 4 hrs and 2 hrs after treatment with Formalin, LAO and BPL, respectively. The vaccine potency [ED50] was arranged in a descending order from formalin (0.016) to BPL (0.005) and LAO (0.002). The total IgG levels, Neutralizing Index (NI) and Interferon levels were significantly increased compared to those detected after immunization... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Rift Valley fever; Inactivant; Humoral immunity; Interferon; Interleukins; LAO. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132016000100345 |
| |
|
|
| Duvic, B.; Jouan, V.; Essa, N.; Girard, P-a; Pages, S.; Khattar, Z. Abi; Volkoff, N-a; Givaudan, A.; Destoumieux-garzon, Delphine; Escoubas, Jean-michel. |
| An antimicrobial peptide (AMP) of the cecropin family was isolated by HPLC from plasma of the insect pest, Spodoptera frugiperda. Its molecular mass is 3910.9 Da as determined by mass spectrometry. Thanks to the EST database Spodobase, we were able to describe 13 cDNAs encoding six different cecropins which belong to the sub-families CecA, CecB, CecC and CecD. The purified peptide identified as CecB1 was chemically synthesized (syCecB1). It was shown to be active against Gram-positive and Gram-negative bacteria as well as fungi. Two closely related entomopathogenic bacteria, Xenorhabdus nematophila F1 and Xenorhabdus mauleonii VC01(T) showed different susceptibility to syCecB1. Indeed, X. nematophila was sensitive to syCecB1 whereas X. mauleonii had a... |
| Tipo: Text |
Palavras-chave: Humoral immunity; Innate immunity; Immunosuppression; Lepidopteran; Invertebrate. |
| Ano: 2012 |
URL: http://archimer.ifremer.fr/doc/00086/19728/17485.pdf |
| |
|
| |
|
|
| Mesquita Jr,D.; Cruvinel,W.M.; Resende,L.S.; Mesquita,F.V.; Silva,N.P.; Câmara,N.O.S.; Andrade,L.E.C.. |
| The traditional concept that effector T helper (Th) responses are mediated by Th1/Th2 cell subtypes has been broadened by the recent demonstration of two new effector T helper cells, the IL-17 producing cells (Th17) and the follicular helper T cells (Tfh). These new subsets have many features in common, such as the ability to produce IL-21 and to express the IL-23 receptor (IL23R), the inducible co-stimulatory molecule ICOS, and the transcription factor c-Maf, all of them essential for expansion and establishment of the final pool of both subsets. Tfh cells differ from Th17 by their ability to home to B cell areas in secondary lymphoid tissue through interactions mediated by the chemokine receptor CXCR5 and its ligand CXCL13. These CXCR5+ CD4+ T cells are... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Autoimmune diseases; Tfh; Lymphoid tissue; Humoral immunity. |
| Ano: 2016 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000500302 |
| |
|
|
| Porto,ML; Givisiez,PEN; Saraiva,EP; Costa,FGP; Moreira Filho,ALB; Andrade,MFS; Brandão,PA; Guerra,RR. |
| ABSTRACTThe objective of this study was to evaluate the effects of 1% dietary glutamic acid on the body weight, intestinal morphometry, and anti-Newcastle antibody titers of broiler chickens submitted to heat stress. One-d-old male broiler chicks (n=120) were distributed according to a 2 x 2 factorial design with two environmental temperatures (thermoneutral or heat stress) and two diets (with 0 or 1% glutamic acid). Heat stress temperature was constantly maintained (24h/day) 5 ºC higher than the thermoneutral temperature. Diets supplied the nutritional requirements of broilers in the pre-starter (1 to 7d) and starter (8 to 21d) phases. Birds were vaccinated against Newcastle disease on d 7 via eye drop. On days 5, 10, 15, and 20, individual body weight... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Amino acid; Duodenum morphology; Environmental temperature; Humoral immunity; Heat stress; Performance.. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-635X2015000300355 |
| |
|
| |
|
| |
|
|
|
